Madecassic acid ( —— )

产品货号. M18146 CAS No. 18449-41-7

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

产品询价大包装询价加入购物车

产品名称

Madecassic acid
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

羟基积雪草酸是从积雪草的全草中提取的。
产品描述

Madecassic acid is extracted from the whole herb of Centella asiatica.
体外实验

Western Blot Analysis Cell Line:RAW 264.7 murine macrophage cell Concentration:50, 100, 150 μM Incubation Time:24 h followed by LPS (1 μg/mL) treatment for 4 h Result:Inhibited LPS-induced iNOS and COX-2 protein expression i in a dose -dependent manner.
体内实验

Animal Model:Colitis mice induced by2.5% DSS Dosage:25?mg/kg/day Administration:Oral gavage (p.o.) , 10 days Result:Decreased the number of γδT17 cells in the colons.Reduced the expression of IL-17 in colon tissues.
同义词

——
通路

Others
靶点

Other Targets
受体

Others
研究领域

Others-Field
适应症

——

CAS Number

18449-41-7
分子量

504.71
分子式

C30H48O6
纯度

>98% (HPLC)
溶解度

In Vitro:?DMSO : 62.5 mg/mL (123.84 mM)
SMILES

C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(C[C@H]([C@@H]3[C@@]4(C[C@H]([C@@H]([C@@]3(C)CO)O)O)C)O)C)[C@@H]2[C@H]1C)C)C(=O)O
化学全称

——

1. Zhang H, et al. J BUON. 2014 Apr-Jun;19(2):372-6.

计算器

产品手册

关联产品

Hydroxy-gamma-sansho...

Hydroxy-γ-sanshool is a pungent compound, it can cause oral numbness.
m-PEG16-Br

m-PEG16-Br 是一种基于 PEG 的 PROTAC 连接体，可用于 PROTAC 的合成。
2-Carboxybenzaldehyd...

The major peak of 2-Carboxybenzaldehyde reductase activity in human liver co-purifies with hAFAR protein. Sulphydryl substances and some proteins play important roles in preserving the molecular and catalytic properties of 2-Carboxybenzaldehyde reductase.